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rhil 17b  (R&D Systems)


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    R&D Systems rhil 17b
    Rhil 17b, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rhil 17b/product/R&D Systems
    Average 93 stars, based on 1 article reviews
    rhil 17b - by Bioz Stars, 2026-05
    93/100 stars

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    rhil 17b  (R&D Systems)
    93
    R&D Systems rhil 17b
    Rhil 17b, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rhil 17b/product/R&D Systems
    Average 93 stars, based on 1 article reviews
    rhil 17b - by Bioz Stars, 2026-05
    93/100 stars
    		  Buy from Supplier
    rhil-17b  (R&D Systems)
    90
    R&D Systems rhil-17b
    <t>IL-17B</t> stimulation of IL-17BR can drive migration and metastasis. (A) Expression of il-17br was analyzed using qRT-PCR. Metastatic cells were compared with matched primary tumors. N=3 except for the SUM1315-BP2 mouse bone data point where too few metastases inhibited significance. (B) Serum-starved SUM1315, SUM1315-BP2 and MDA-MB-231 BCCs showed a dose-dependent reaction <t>to</t> <t>IL-17B</t> stimulation after 6-hours. No increase in migration was observed for MCF7 BCCs. (C) Serum-starved SUM1315 and MDA-MB-231 BCCs (mock infected or infected with lentivirus to overexpress il-17br cDNA) migrated for 6-hours on transwell migration assays. (D) Bioluminescent imaging of human bone fragments, lungs, and livers was used to assess metastasis frequency.
    Rhil 17b, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rhil-17b/product/R&D Systems
    Average 90 stars, based on 1 article reviews
    rhil-17b - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier

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    IL-17B stimulation of IL-17BR can drive migration and metastasis. (A) Expression of il-17br was analyzed using qRT-PCR. Metastatic cells were compared with matched primary tumors. N=3 except for the SUM1315-BP2 mouse bone data point where too few metastases inhibited significance. (B) Serum-starved SUM1315, SUM1315-BP2 and MDA-MB-231 BCCs showed a dose-dependent reaction to IL-17B stimulation after 6-hours. No increase in migration was observed for MCF7 BCCs. (C) Serum-starved SUM1315 and MDA-MB-231 BCCs (mock infected or infected with lentivirus to overexpress il-17br cDNA) migrated for 6-hours on transwell migration assays. (D) Bioluminescent imaging of human bone fragments, lungs, and livers was used to assess metastasis frequency.

    Journal:

    Article Title: Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis

    doi: 10.1158/0008-5472.CAN-10-1254

    Figure Lengend Snippet: IL-17B stimulation of IL-17BR can drive migration and metastasis. (A) Expression of il-17br was analyzed using qRT-PCR. Metastatic cells were compared with matched primary tumors. N=3 except for the SUM1315-BP2 mouse bone data point where too few metastases inhibited significance. (B) Serum-starved SUM1315, SUM1315-BP2 and MDA-MB-231 BCCs showed a dose-dependent reaction to IL-17B stimulation after 6-hours. No increase in migration was observed for MCF7 BCCs. (C) Serum-starved SUM1315 and MDA-MB-231 BCCs (mock infected or infected with lentivirus to overexpress il-17br cDNA) migrated for 6-hours on transwell migration assays. (D) Bioluminescent imaging of human bone fragments, lungs, and livers was used to assess metastasis frequency.

    Article Snippet: For IL-17B migration assays, 20 ng/mL rhIL-17B (R&D Systems) was added to BCCs before seeding.

    Techniques: Migration, Expressing, Quantitative RT-PCR, Infection, Imaging